Validated UV-spectrophotometric method for the estimation of naftopidil in bulk and tablet formulation

Research Article

Kiran Aarelly, Khaggeswar Bhee

Abstract

New, simple, sensitive, cost effective and reproducible UV-spectrophotometric method was developed and validated for the estimation of naftopidil in bulk and tablet formulations. Naftopidil was estimated at 280 nm using acetonitrile-hydrochloric acid (pH 1.2, 100 mM) (25:75, v/v) as solvent system. This method was tested and validated for various parameters as per USP requirements and ICH guidelines.

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