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Subba Rao Chamakuri*, Sabil Ba

Abstract

The Ethanolic extract of Tradescantia spathacea leaves was investigated for anti-helmintic activity using earthworms (Pheretimaposthuma). Various concentrations (10-20 mg/ml) of plant extract were tested in the bioassay. The reference standard drug used is albendazole (10 mg/ml) and Tween 80 as control. Establishment of paralysis time and death time of the worms were recorded. Extract exhibited significant anthelmintic activity at the concentration of 20 mg/ml. The result shows that ethanolic extract possesses anthelmintic activity. Therefore, the anthelmintic activity of the ethanolic extract of Tradescantia spathacea has been reported for the first time.

Relevant Publications in Journal of Chemical and Pharmaceutical Research