Topical treatment with yellow-ipe extract (Tabebuia aurea) in wound healing by secondary intention in rats

Fabiani Tenór

Abstract

The objective of the research was to study the healing in vivopotential, from the topical administration of the ethanol extract of the leaves of Tabebuia aurea (EETA). Twenty-sevenRattusNorvegicus Albinus Wistar were used in this study, divided into three groups with n = 9. The animals were followed for fourteen days, the post-production of the wounds. Group 1 was treated with 5% dexpanthenol, group 2 with based cream and group 3 was treated with 5% EETA. It was performed a macroscopic assessment of wounds, to monitor the size of the injury area, contraction percentage, histopathology analysis and biochemical evaluation. The results showed that the evolution of the group treated with EETA showed no scar development better than control groups, and presenting crust on the macroscopic assessment and the absence of totalre-epithelialization, at the end of fourteen days of treatment