The Study of Novel Sulfilimines as Potential Insects Modulators

 Sha Zhou and Zhengmin

Abstract

This paper describes the novel sulfiliminyl structures as potential control of the Ca2+ influx within the Ryanodine Receptor of insect body. Referring to commercial Flubendiamide structural composition, N-cyano, N-trifluroacetyl and N-acylamino sulfiliminyl moieties were firstly introduced into dicarboxamides scaffolds. The chiral sulfilimines especially exhibited significant insecticidal activities. The investigation of chirality impact on bioactivity was also systemically studied.