The sole or key enzymes of purine and pyrimidine metabolisms might direct the organisms to the cells proliferation

Danielyan KE

Abstract

Cancer development and regenerative cells proliferation are two apposite and self-excluded processes in the organism. However, the classical biochemical pathways of purine and pyrimidine metabolism basically are the same. We presented over years results, evidencing, inhibition of the cells purine and pyrimidine catabolism via influence on the key regulative enzymes and activation of their synthesis might consequently trigger cell proliferation.

Relevant Publications in Journal of Biomolecules and Biochemistry