Research Article
Andika Dwi Mahendra, Kuswandi
Abstract
Background: Sepsis incidence which related with morbidity and mortality is globally increasing. Sepsis occurs because of severe infections. Sepsis has lifethreatening potential with organ dysfunction complication, septic shock, and death. Alteration of resistance pattern always changes at certain period. The aim of the study is to investigate the bacteria pattern and its resistance from adult sepsis patient at Dr. Moewardi General Hospital. Methods: Isolated bacteria from adult sepsis patient’s blood at Dr. Moewardi General Hospital. 7 bacteria isolates were taken from blood of adult sepsis patient (September - October 2014) and 46 bacteria isolates of secondary data (January - March 2014) at Dr. Moewardi General Hospital. Bacteria isolation was performed based on standard Laboratory of Microbiology of Dr. Moewardi General Hospital. 7 bacteria isolates were tested by using disc diffusion antibiotic on Mueller Hinton and coupled by 46 secondary data. Results: The bacteria pattern from adult sepsis patients were Staphylococcus haemolyticus (15.09%), Staphylococcus hominis (15.09%), Escherichia coli (13.21%), and Acinetobacter baumannii (11.32%). Resistance pattern of bacteria on adult sepsis with level of resistant more than 50% as Staphylococcus haemolyticus (ciprofloxacin, erythromycin, levofloxacin, moxifloxacin, and gentamicin), Escherichia coli (gentamicin, ciprofloxacin, and levofloxacin), and Acinetobacter baumannii (gentamicin, ciprofloxacin, levofloxacin, and ceftazidime) Conclusions: Based on this research, revealed that sepsis tended to be caused by Gram-positive than Grampositive, 54.71% and 45.29% respectively.