Review Article
Dimitri D, Arduini R, Galetto
Abstract
This review summarizes the existing available data on the use of transcranial Direct Current Stimulation (tDCS) as a treatment for migraine symptoms both with and without aura. 27 studies were examined and 5 were included in the review (which satisfied the inclusion criteria, i.e., duration of tDCS, intensity of stimulation, type of stimulation and stimulated cerebral area). The visual cortex was stimulated in 4 of the 5 analyzed studies. All these studies reported a 1 mA current flowing (anodic stimulation), with a duration of 15-to-20 minutes but not the same montage protocol. The sessions were then repeated 2-4 times a week, for a variable period of 4-8 weeks. The other study adopted a cathodic stimulation on the primary motor cortex with an intensity of 2 mA. Both anodic and cathodic stimulations on the visual cortex provided important results: repeated series of preventive anodic stimulations resulted in a decrease in the regularity of migraine attacks, duration and pain perceived by the patient. The study about the stimulation of the motor cortex pointed out a decrease in the regularity and duration of attacks. Overall, the tDCS can be considered as a useful instrument, capable of bringing benefits to patient suffering from migraine; however, the duration of the obtained benefits was limited in all the cases reported and the size of sample was too small. Further studies are therefore needed to better comprehend the mechanisms involved in the pathogenesis of migraine symptoms.