Nazanin Foroutan
Abstract
Ciprofloxacin is a broad-spectrum antibiotic from fluoroquinolones which are used to treat gram negative and positive bacterial infections. In last twenty years, tendinopathy is a worrying side effect. The side effects of tendon disorders including pain on tendon, angle tenderness, tendinitis and tendon rupture risk. Based on these symptoms various cases are shown and calculated. After several weeks pause in ciprofloxacin treatment the symptoms of tendon disorders are reduced. Ciprofloxacin is a broad spectrum antibacterial agent against gram negative bacteria and also gram positive (recently), anaerobic bacteria which belongs from the class of fluoroquinolones which are used for treatment of different bacterial infections ranging from urinary tract infections to respiratory tract infections [1-3]. It functions by inhibiting DNA gyrase and a type II topoisomerase, topoisomerase IV, necessary to separate bacterial DNA, thereby, inhibiting cell divisions [4-6]. Common side effects of fluoroquinolones are gastrointestinal effects (such as vomiting, nausea and diarrhoea), central nervous system reactions (from mild one such as sleeplessness, headache and dizziness to sever). Also Ciprofloxacin can cause skin tumors due to photosensitivity