Systemic Lupus Erythematosus: An Autoimmune Disease with Multiple Clinical Ways of Presentation

Guzmán-García Santiago

Abstract

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that can affect any organ in the body. Therefore, the clinical manifestations that patients present are highly variable, they can have mild conditions such as localized skin or joint manifestations, up to more serious conditions, such as kidney, hematological or central nervous system conditions. The SLE is characterized by abnormal production of autoantibodies; the most characteristic are Antinuclear Antibodies (ANA), and their specificities, and antiphospholipid antibodies. In this review, we present a clinical case of SLE with particular clinical manifestations, with the aim of providing the reader with key findings in this pathology to improve the precision of the diagnosis early and thus initiate treatment in a timely manner.