Synthetic, spectral, magnetic and antibacterial studies of schiff base transition metal complexes of bis-[(1-(5-chloro-2-hydroxyphenyl) ethanone)-diaminopropane]

Abdul Wajid, Naushad Zubair an

Abstract

A Schiff base bis-[(1-(5-chloro-2-hydroxyphenyl) ethanone)-diaminopropane] was synthesized via the reaction of 1- (5-chloro-2-hydroxyphenyl) ethanone) with 1, 3 diaminopropane and investigated by CHN elemental analyses, IR spectra, 1H NMR. The infrared spectral data exhibited the main positions of functional groups present in the Schiff base. 1H NMR data reveals that all signals belonging to the main functional groups in the Schiff base. The Schiff base complexes have been synthesized from CHPEDAP with Mn(II), Co(II), Cr(III), Ni(II), Cu(II), Zn(II) and Cd(II) ions and characterized by elemental analyses, spectral (1H NMR, FT-IR and electronic spectra), magnetic susceptibility measurements. The Schiff base and the complexes have been screened for antibacterial activity against E. coli, S. typhy, S. aureus, P. aeruginosa and K. pneumonie bacterial species using Agar well diffusion method. The study shows that the Schiff base complexes show more antibacterial activity compared to ligand.