Synthesis, spectroscopic investigation and antimicrobial studies on some Schiff base complexes of Cu(II) and Ni(II)

S. Ajith Sinthuja and S. Sudha

Abstract

Two new metal complexes of Cu (II) and Ni (II) ions with a Schiff base derived from Glutaraldehyde and L-Valine have been investigated. The resulting complexes were characterized by elemental analysis, X-ray Diffraction studies, thermogravimetric analysis, Uv/vis IR, 1H NMR spectral studies, molar conductance, magnetic susceptibility measurements and antimicrobial activity. The molar conductance measurements indicates that the complexes are non electrolytes. The IR data demonstrate the tetradentate binding of the ligand. The XRD data shows that CuL1 and NiL1 complexes were microcrystalline in nature. The invitrio antimicrobial activity of the compounds is tested against the bacteria Klebsiella sps, Escherichia coli, Staphylococcos aureus and fungi Candida sps, Aspergillus niger and Aspergillus fumingatus by the Disc diffusion method. The complexes show stronger antimicrobial activity than the free ligands.