Synthesis, spectral studies and antibacterial screening of some novel derivatives of 2-Pyrrolidinones based on Schiff base

S. D. Sutariya1, K. A. Parmar1

Abstract

2-Pyrrolidinones are one of the heterocyclic compounds with very important biological activites. In this view, it was proposed to synthesize some novel 2-Pyrrolidinones from Schiff bases. Here the synthesis of 2-Pyrrolidinones using 1-N-phenyl-3-phenyl-4-formyl pyrazole (PFP), Schiff bases and succinic anhydride under basic condition in presence of ethanol. The structures of synthesized were assigned on the basis of elemental analysis, IR and 1H NMR spectroscopy data. These compounds were screened for their anti-bacterial activity