Synthesis, Optimization and Evaluation of Substituted Quinolines by Solvent and Catalyst Free Conditions as a Green Protocol

K Rama Devi, D Ashok, KSK Rao

Abstract

A straightforward, exceedingly and environmentally method for the synthesis of quinolines have been developed by solvent free and catalyst free conditions as a green protocol. This method avoids environmentally destructive predictable organic solvents. Therefore; this Method provides a green and much enhanced protocol over the existing methods. We have developed an eco-friendly process for the synthesis of functionalized quinolines from imines with styrene. The proposed quinolines were synthesized and evaluated for their pharmacological activities like anti-helmenthic activity.

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