Research Article
Vanita A Navale, S.B. Zangade,
Abstract
New chalcones (3a-k) were synthesized from substituted 2-hydroxy acetophenones and 2- benzyloxy, 3-benzyloxy-4-methoxy, 4-benzyloxy-3-methoxy benzaldehyde via claisen-schmidt condensation. Further these chalcones converted into corresponding flavones (4a-k) by oxidative cyclization of chalcones using DMSO-I2. The structure of synthesized compound was confirmed by elemental analysis and spectral data. The newly synthesized compounds were screened for antimicrobial activity against E-coli, S. Typhi, Staph. aureus, and Aspergillus niger.