Synthesis of polycyclic heterocycles through domino Knoevenagel intramolecular hetero Diels–Alder reaction under solvent free and microwave irradiation conditions

M. M. V. Ramana, Vishwanath V.

Abstract

Benzopyrano-pyrano-pyrazoles were synthesized through domino Knoevenagel intramolecular hetero Diels–Alder reaction under solvent free and microwave irradiation conditions. These compounds have the potential to exhibit biological activity. A high degree of chemoselectivity was achieved by the application of microwave irradiation. This green chemistry protocol showed to be very useful under milder reaction conditions.