Synthesis of Organoclay and its Applications in Electrochemical Detection of Paracetamol

Valery HambateGomdje, Abdoul N

Abstract

The aim of this work is to synthesize by cationic exchange reaction organoclays by exfoliation after modification of clay with cetyltrimethylammonium ions (CTA+) and their use as an electrode material for the detection of Paracetamol. The physicochemical properties of modified and unmodified clay mineral are first analyzed by particle size analysis, XRD, BET, FTIR, thermal analysis (TGA and DTA), 29Si NMR, 27Al NMR and TEM. The results showed that the surface of clay successfully reacted with cetyltrimethylammonium bromide (CTAB) and this significantly enhanced electrochemical reactivity. This electrochemical sensor exhibited excellent analytical performance for Paracetamol detection at physiological pH with detection limit of 23 μM, linear range of 10-80 μM (R2=0.9825).