Synthesis of 1,3-disubstituted pyrazoles using ionic liquid

Chandrashekhar G. Devkate, Kha

Abstract

Pyrazoles are well known five-membered nitrogen containing heterocyclic compounds possessing diverse bioactivities and are used extensively in pharmaceutical industry. Here we have used ionic liquid as a solvent which is highly efficient and environmentally friendly. We were interested in synthesizing 1,3-disubstituted pyrazoles using cinnamaldehyde as it gives complete regioselective product with only single isomers are obtained and the method gave us a excellent yields.

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