Synthesis, Characterization of β- amino ketone Complexes and Study of their Antibacterial Activity

Rahul Watpade, Parag Tandale,

Abstract

One pot mannich reaction of aromatic amine, aromatic aldehyde and aromatic ketone, in preference of catalytic amount of sulphamic acid furnish β- amino carbonyl compounds in good yields. These β- amino ketone was reacted with metal acetate of Co (II), Ni(II) and Mn (II), form square planer complexes in good yields. All the ligand and metal complexes obtained were well characterized by spectroscopic and analytical methods. The new metal complexes were tested for antibacterial activity against three pathogenic bacteria. B.subtilis, E.coli and B.cereus show good activity.