Synthesis and microbial assay of maltosyl tetrazino benzothiazoles

Research Article

Renu B. Ghayalkar and Shirish

Abstract

A new series of 3-oxo-4- hepta-O-benzoyl-β-D-maltosyl-(1,2,4,5)-tetrazino-(2,1b)-benzothiazoles by the oxidative cyclisation of 1-hepta-O-benzoyl-β-D-maltosyl-4-benzothiazolyl semicarbazides. The identities of these newly synthesized compounds have been established on the basis of usual chemical transformations and IR, 1H NMR, 13C NMR and Mass spectral studies and these compounds were screened for their antibacterial activity against pathogens like E. coli, S. aureus, P. vulgaris, S. typhi, K. pneumoniae, Ps. aeruginosa and for antifungal activity against T. harzianum and Verticillium species to get potent bioactive molecule.

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