Synthesis and in vitro bioevaluation of 1,5-Bis(5-substituted benzimidazole) alkanes as antileishmanial agents

Mahesh Verma, Anil Bhandari an

Abstract

Some 1,5-bis(5-substituted benzimidazole)alkanes (4a-4f, 5a-5f & 6a-6d) were synthesized from 3a-3f substituted benzimidazole and screened towards in vitro antileishmanial activity profile. Some of compounds such as 4c, 5c, 6c & 6d displayed good antileishmanial activity.