Research Article
Vimal Patel, Nilay D Bhatt, Pr
Abstract
The synthesis of 5H-dibenzo(b,f)azepine-5-carboxylic acid [3-chloro-2-(substituted phenyl)-4-oxo-azetidin-1-yl]- amide (2a-d) was achieved by the reaction of (1a-d) with chloroacetyl chloride in presence of triethylamine. Three substituted aryl piperazine derivatives (R1-3) were prepared and they were reacted with (2a-d) to give 5Hdibenzo( b,f) azepine-5-carboxamido-4’-aryl-3’-aryl piperazine-2’-azetidinone (3a-l). The products have been characterized by elemental analysis, IR, 1H NMR, 13C-NMR and mass spectral studies