Synthesis and characterization of some 1,4-diazepines derivatives

K. Sudarshan Rao, K. Nageswara

Abstract

Synthesis of new compounds possessing 7-membered rings with two heteroatom a 1,4-diazepines having fused heterocyclic ring of coumarin and thiophene and cyclic secondary amine as a side chain. Substituted 8-amino-10- methyl chromeno [3, 4-b] thieno [2, 3-e] [1, 4] diazepin-6(12H)-one hydrochlorides treated with cyclic secondary amine (N-methyl, N-ethyl, N-phenyl and N-benzylpiperazine) in potassium carbonate and toluene at reflux condition.