Synthesis and Characterization of Deshydroxy Posaconazole

Ravi Kumar K, Srinivasa Red

Abstract

Posaconazole is a triazole antifungal drug and used for the treatment of infections caused by fungi. During the process development of posaconazole, the process related impurity deshydroxy posaconazole was identified as a critical impurity along with the final API. The present work describes the synthesis and characterization of this deshydroxy posaconazole.

Relevant Publications in Organic Chemistry: Current Research