Synthesis and characterization of amino acid (phenylalanine) schiff bases and their metal complexes

Faliah Hassan Ali Al-Jeboori,

Abstract

Schiff bases derived from the condensation of benzaldehyde or acetone and the amino acid phenylalanine in basic media using sodium hydroxide as a catalyst have been synthesized and their Co (II), Ni (II) and Cu (II) complexes have been prepared. The Schiff bases and their complexes that been prepared, were analyzed and characterized by using different techniques, such as elemental analysis, infrared and electronic spectra. The IR spectra, UV bands and atomic absorption analysis show that the Schiff base ligand forming chelates with 2 : 1 (ligand : Metal) stoichiometry. Some of prepared metal complexes were evaluated for in-vitro antibacterial activity against Negative and Positive Bacteria. The complexes showed significant anti bacterial activity.

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