Synthesis and Biological Screening of Some New Substituted 1-Acetyl Benzimidazol-2-yl Methyl Isoindoline-1,3-Dione Analogs as Anti-Microbial Agents

Nadia TA Dawoud, Fivian Farouk

Abstract

The present work deals with the synthesis of 2-(1-acetyl-1H-benzimidazol -2-yl) methyl) isoindoline-1,3-dione (3), used as a key synthons to synthesize a series of some new heterocyclic compounds incorporating benzimidazole moiety. The newly synthesized compounds are characterized by their elemental analysis, IR, 1H, 13C-NMR and mass spectral data and assessed for their antimicrobial activity.

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