Synthesis and biological evaluation of new amino derivatives of 1,4-naphthoquinone

Oksana Figurka*, Semen Khomyak

Abstract

Synthesized ranks of new biologically active compounds by nucleophilic substitution of chlorine atom in the amino acid chloride derivatives of 1,4-naphthoquinone. All structures characterized with standard methods of chemical analysis and spectroscopic techniques. Experimental biological screening of synthesized compounds carried out. Among the newly synthesized compounds detected non-embryotoxic fungicides and bactericides, which does not cause oxidative stress.