Synthesis and biological activity studies of novel heterocyclic compounds

C. A. M. A. Huq and S. Sivakum

Abstract

We herein report the synthesis of the novel heterocyclic compounds (1),(2)&(3), by the Grignard addition of 2 thiophenyl magnesium bromide to phenanthrene-1,2- dione, benzil and acenaphthene-1,2-dione respectively The synthesized novel heterocyclic compounds were screened for antibacterial, antifungal and cytotoxic activity studies.