Original Articles
P. Lavanya, K. Veena Vani, K.
Abstract
4-Aminopyrimidine-5-carbonitrile (1) underwent facile condensation with various aromatic acid derivatives in the presence of 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimidehydrochloride (EDC.HCl) and small catalytic amount of TEA afforded corresponding substituted-N-(5- cyanopyrimidin-4-yl)benzamide derivatives 3a-j. They were characterized by IR, 1H, NMR and Mass spectral data. All the compounds were screened for anti-microbial, anti-oxidant activities.