Synthesis and antimicrobial activity of pyrazine carboxamide derivatives

Nisha Tewatia*1, Abida2 and K.

Abstract

A series of pyrazine carboxamide derivatives was synthesized by the condensation of pyrazine-2-carboxylic acid chloride with various substituted amino pyridines. The structures of these derivatives were elucidated on the basis of IR, 1H-NMR and mass spectral data. These compounds were further evaluated for their antimycobacterial activity and antifungal activity