Surveying the effect of hydroalcoholic tarooneh (spathe of phoenix dactylifera) extract on anesthesia and EEG barin waves

Rahimi S., Alaei H., Reisi P.,

Abstract

No single anesthetic drugs could provide all the characteristics of an ideal general anesthesia, but a combination of intravenous drugs given produced the desired balanced anesthetic. Tarooneh (spathe of phoenix dactylifera) is a hard covering of date palm pollen that torn and open in pollination season, in south and west of Iran since a long time people take tarooneh's extract as a sedative and calmative substance, according to its proved effect on pain and its usage it is examined on anesthesia and EEG brain waves. Pharmacological maceration technique has been used for the tarooneh extract and the Solvent was 70% ethanol. Animals divided to 4 groups for anesthesia analysis and 4 groups for EEG analysis, in anesthesia analysis one of the groups just injected by chloral hydrate and 3 other groups received doses 62.5, 125 and 250 mg/kg tarooneh extract after chloral hydrate. 4 other groups of EEG injected by these three doses of extract and saline for control group after anesthetizing. The mean anesthesia time in the ch+250 group (the dose 250 mg/kg) was more than the other groups. In fact we can say time of anesthesia in this 4 group is significantly different. By doing a posttest it has shown that ch+250 and ch+125 groups are significantly different from 2 other groups. This result in EEG brain wave is similar and in 125 and 250 mg/kg significant difference was observed. This study showed the efficacy of tarooneh in anesthetized rats that increased anesthesia time so its sedative affect can be helpful in sleeping and anesthesia.

Relevant Publications in Journal of Chemical and Pharmaceutical Research