Survey cytotoxicity and genotoxicity of hydroalcoholic extract of Stevia rebaudiana in breast cancer cell line (MCF7) and human fetal lung fibroblasts (MRC-5)

Mohammad Shokrzadeh, Farnaz Ra

Abstract

Breast cancer is the most commonly diagnosed cancer in women and is the second leading cause of cancer death among them. Chemotherapy is one of the commonly used strategies in treatment. This therapy is usually associated with adverse side effects. Isolating and identifying potent anti- Tumor Compounds from Medicinal Plants motivated researchers to find plant species for anti- Tumor Effects. Therefore, finding natural compounds from plants may provide an alternative cancer treatment. Stevia rebaudiana is an important medicinal plant in the world.