Studying the cell- internalization pathways of PLGA nanoparticles and the derivitives obtained from Its incorporation with carbonhydrates

Abdülkadir Bahadı

Abstract

Nano-micelles consisting of amphiphilic polymer “poly lactide co glycolid (PLGA)” have been named as “Gold Standart” by FDA and have been used in many targeted cancer therapy studies, however, the cell internalization pathways of these nanoparticles into the cancer cell are not fully known. Since the entry of the nano-particle into the cell will greatly alter the effectiveness of the therapeutic agent payload, the investigation of this subject is of great importance for effective targeting.