Study of human-like collagen adsorption on true bone ceramic

Yajing Wang, Daidi Fan, Junfen

Abstract

An ideal bone graft material should have the characteristic of good biocompatibility. In this study, human-like collagen (HLC) was introduced into a scaffold of true bone ceramics (TBC) to structure a good bioactive scaffolds[1,2]. The cellular structure of scaffold and pore size was examined through scanning electron microscopy (SEM). The pores with diameter ranging from 300 to 500um distributed evenly in the scaffolds, and these pores were interconnected with each other. This study also was conducted to find the optimum condition of TBC absorbtion HLC. Experimental results showed that when the HLC solution pH was 4, concentration was 20 mg/ml and the temperature was 50 ℃, the HLC adsorption can reach the largest amount of 26.8 g/mg TBC. TBC/HLC scaffolds is expected to become a good bone defect repair material.

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