Studies on synthesis, antibacterial screening and the mass fragmentation of 1- (4,6-dimethylbenzothiazolyl)-3,5-disubstituted-1,2,4-1H-triazoles

*D. K. Swamy, **S. V. Kuberkar

Abstract

Some substituted benzothiazolyl triazoles are synthesized from 2-hydrazino-4,6- dimethylbenzothiazole treating this starting material with alkyl/aryl/heteryl nitrile in presence of anhydrous aluminium chloride yielded 1-(4,6-dimethylbenzothiazolyl)-3,5-alkyl/aryl or heteryl 1,2,4-1H triazole. Mechanism of reaction, its mass fragmentation pattern and antibacterial activity are reported.