Statistical Optimization of Culture Conditions for L-Methionine Production by Corynebacterium glutamicum X300

Subhadeep Ganguly and Kunja

Abstract

Statistical optimization was done for L-methionine production by Corynebacterium glutamicum X300 using Response Surface Methodology emphasizing Central Composite Design with different variables. Maximum production of L-methionine (52.1 mg/ml) was obtained with 72 h of incubation.