Original Articles
Gopi Patel, Payal Chauhan and
Abstract
A UV- Spectrophotometric method has been developed for the determination of Gatifloxacin and Flurbiprofen Sodium in their pharmaceutical formulation.The wavelength method involved solving simultaneous equations based on measurement of absorbance at two maximum wavelengths 245 nm and 293 nm for Flurbiprofen Sodium and Gatifloxacin respectively. The method was validated for various parameters according to ICH guideline. The linear regression analysis data for the calibration plots showed good linear relationship in the concentration range of 6-18 μg/ml and 0.6 – 1.8 μg/ml and correlation coefficient was found to be 0.9984 and 0.9995 for Gatifloxacin and Flurbiprofen Sodium respectively.