SARS-CoV-2: A Systematic Review

Poonam Goel*, Vaibhav Gupta

Abstract

Introducton: SARS-CoV-2 outbreak in China has spread its roots to almost all the countries around the world and infected lakhs of individuals. To summarize the demographical, clinical, laboratory, radiographic features, comorbidites, and treatment strategies of confrmed SARS-CoV-2 infecton, the systematc review was designed. Sources: PubMed and Google Scholar artcles were searched for English-language artcles published between January and April 2020. Data: A total of 156 artcles were identfed by the literature search from which53full text artcles met the inclusion criteria. Afer quality assessment using variouschecklists, 15artcles were included. Study selecton: Artcles included in the review presented studies from four contnents of world with majority from China Mean age of patents with corona infecton was 49.3 years, with 56% males and 44% females. Along with this 8% of the individuals were reported with smoking. Major clinical symptoms were fever, dry cough, shortness of breath, fatgue and around 27.5% patents presented with comorbidites. Choice of treatment was antviral therapy along with symptomatc therapy. Conclusion: Itcan help clinician to diagnose and plan treatment for SARS-CoV-2 patent which appears to be highly communicable from the existng epidemiological data with varying fatality rate. More rapidly the cases are detected, isolated, and traced; the more efcacious will be the preventon strategies for any country to evade community transmission.

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