Role of Propolis in Osteointegration Enhancement in Allograft Autoclaved Implanted in Femur of Dogs

Abdellatif Boudra, Mohamed

Abstract

The orthopedic surgeon is often faced with the loss of bone substance indiaphyseal region of long bones. Our study is based on a biological approach to the filling of segmental bone loss by implanting an autoclaved orthotopic allograft of one centimeter length covered and uncovered with propolis in the femoral diaphysis. The experiment involved eight adult dogs, from local breed and different sex; split into two groups. An autoclaved allograft without propolis was implanted for the first animals group then the same graft this time covered with a thin layer of propolis has been implanted to the second animals group. The aim of our study is to determine if the propolis accelerates the osteointegration of the allograft covered with propolis, to follow up that process radiologically until obtaining a total consolidation. The results show that the use of a graft covered with propolis enhance and accelerate the osteointegration process; it has been demonstrated by an early passage of the callus at both proximal and distal interfaces, with an average duration of four weeks and eight weeks respectively.

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