Reduction of Chiral Amino Acids Based on Current Method

Yuqing Cao and Guangyu Yang

Abstract

This paper aims to introduce a simple and convenient method for the industrial production of chiral amino alcohols. Based on the current reduction of chiral amino acids, this work can efficiently simplify the experimental procedure by using Li as reducing agent and AlCl3 as auxiliary material to activate the carboxyl group of amino acids . In order to show the practicability of our method, L-phenylalanine and other several kinds of chiral amino acids were applied to this reduction, and through suitable condition setting, the yield of our tests reached 74.8~91.4%.