Preparation of collagen wound-healing membranes

Hua Yang, Xuexu Chen, Zibin Sh

Abstract

Collagen can be extracted from the fresh pigskin through enzymatic hydrolysis. Collagen, together with various Chinese herbal extracts including Callicarpa bodinieri, Glycyrrhiza uralensis, and Zanthoxylum nitidum, are used to prepare collagen wound-healing membranes. In order to make drugs well dispersed in the membrane, Polyvinylpyrrolidone (PVP) is used as the dispersant to prepare drug dispersions by applying solvent evaporation-fusion method. The optimal procedure to prepare the membrane is studied and concluded by experimenting with different proportions of humectant, drugs and dispersants.