PREPARATION AND EVALUATION OF TOPICAL GEL OF NIGELLA SATIVA (KALONJI)

Upasana Bhalani, Ketan Shah

Abstract

The objective of this study was to check the effectiveness of Nigella Sativa against the microbial species Propronibacterium Acnes, to observe the zone of inhibition and to develop a topical formulation of Nigella Sativa for the treatment of Acne Vulgaris. The topical drug delivery system is simple, effective and very useful in treating acne. The gel was formulated using carbopol 940. Thus the gel developed was evaluated for various physico-chemical parameters like its physical appearance, pH, viscosity and homogeneity.

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