Research Article
Rakesh Yadav, Sneha Singh, Div
Abstract
We present in this article syntheses of three new hybrids compounds (7, 10, 13) that were efficiently prepared in two or three steps from our previous prototype 5,6-diaminouracil with the NSAIAs (Diclofenac acid and Indomethacin) and 5-nitro-2-furaldehyde. The histamine chamber-aerosol induced method (5 ml of 1% w/v aerosoled in 1 min) is able to determine that all investigated new hybrids showed stronger bronchospasmolytic properties than their precursors.