Piperidine mediated synthesis of new series of prenyloxy chalcones and flavanones as antibacterial agents

Bhasker N and Suba Reddy B. V

Abstract

The prenylated chalcones 3a-g, 5a-b and 6a-d were synthesized by piperidine mediated condensation of an ethanolic solution of a 4-prenyloxy 2-hydroxy acetophenone 1 with corresponding aromatic or hetero aldehydes. The structures have been established on the basis of elemental (C, H, O) analysis, IR, 1H NMR, Ms spectral data. The compounds 3a-g, 5a-b and 6a-d were screened for antimicrobial activities against a variety of bacterial agent