Pharmacogenetics and Molecular study on BCR/ABL Inhibitors connected with Chronic Myeloid Leukemia; Genotype variability polymorphism among Babylon population

Israa Hussein Noor Hassan1, Al

Abstract

Our study aimed to investigate the association between multidrug resistance BCR/ABL1 gene polymorphisms associated with chronic myeloid leukemia (CML). The BCR/ABL1 oncogene contributes to the progress of CML clones. BCR/ABL played significant roles in the pathogenesis in CML. Expression of BCR-ABL in patients were 88.9%, while in control was 6.7%