Peripartum Cardiomyopathy: It is Possible to Make a Prenatal Diagnosis

James D. Fett

Abstract

Earlier diagnosis of peripartum cardiomyopathy (PPCM) can identify systolic dysfunction in a less severe stage. I urge all providers of medical care to peripartum subjects and all peripartum subjects to become aware of the potential for pregnancy-associated heart failure to develop as well as the possibility of making an earlier diagnosis. Steps in this direction include adding blood tests available to assist with earlier diagnosis of PPCM [serum NT-ProBNP and potentially serum fms-like tyrosine kinase (sFLT-1) or soluble vascular endothelial growth factor receptor-1 to placental growth factor (PlGF) ratio]. In addition, the simple, no cost “Self-Test” for recognizing pregnancy-associated heart failure can be included in routine obstetrical care. Together, they have the potential to help victims of PPCM experience earlier diagnosis with better preserved heart function; and then to reach full recovery using effective evidence-based available treatment, saving many lives of mothers and their unborn or newborn children.