One-pot synthesis of naphtho[2,1-e][1,3]oxazin-2-ones and naphtho[1,2e][1,3][oxazin-3-ones and their transformation into novel condensed heterocyclic systems

Archana Sharma, Shallu Gupta,

Abstract

A series of 4-aryl-3,4-dihydronaphtho-[2,1-e]oxazin-2-ones and another series of 1-aryl-2,3-dihydronaphtho[1,2- e][1,3]oxazin-3-ones have been synthesised using the one pot three component coupling of α-naphthol/β-naphthol, urea and variedly substituted aldehydes and potash alum under solvent free conditions. These naphthoxazinone derivatives were further reacted with various aliphatic and aromatic amines to yield the varied condensed heterocyclic systems.