One-Pot, Four-component Synthesis of Oxime ethers from Cinnamaldehyde, Crotonaldehyde, Hydroxylamine Salt, Potasium carbonate and Alkyl halides

Abdulraman O. C. Aliyu, O. W.

Abstract

Oxime ethers were synthesised in a one-pot, four-component reaction from cinnamaldehyde crotonaldehyde, hydroxylamine hydrochloride, anhydrous sodium carbonate and some alkyl halides. Alkyl halides also served as the solvent of the reaction. The reactions were completed in about 1 hour with yields of 57 to 84%.