Novel synthetic methodology for the synthesis of Ticagrelor

Nitin A. Shimpi, Siva Koteswar

Abstract

Ticagrelor is the first reversible P2Y12 receptor antagonist blocking adenine diphosphate (ADP) induced platelet aggregation with rapid onset and offset of effect [1] [2]. A new methodology for the synthesis of Ticagrelor and its novel intermediates which is useful for the commercial synthesize of Ticagrelor.