Microwave Assisted One Pot Synthesis of Substituted Dihydropyrimidine-2(1H) ones using 5-sulphosalicyclic acid as a Catalyst

Research Article

Nazeruddin N. Gulam Mohammed ,

Abstract

An efficient microwave assisted one pot synthesis of Dihydropyrimidine-2 (1H) from aldehydes, diketones and urea/thiourea using 5-sulphosalicylic acid as a catalyst is described, compared to classical Biginielli reaction the new method has advantage of good yield and short reaction time

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