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Abstract
Our study aims to state the evidence-based effect of the implementation of newborn infant nutrition with prebiotics&probiotics has been demonstrated in changing microflora composition toward the desired breast-feeding pattern&stimulating immune responseSeveral studies performed in the past decades have clearly demonstrated the complexity of gut microbiota composition and the modulatory effect played by several endogenous and exogenous factors on it. Type of feeding in the first months of life appears as one of the most important determinants of the child and adult well-being,and its protective action seems to rely mainly on its ability to modulate intestinal microflora composition at early stages of life